Muira Puama

An Amazonian tonic traditionally used to support energy and sexual vitality.


Muira Puama (Ptychopetalum olacoides) is a shrub native to the Brazilian Amazon whose root and bark have been used traditionally by indigenous communities as a tonic. In folk and herbal medicine it is commonly cited for antifatigue effects and as an aphrodisiac or stimulant, and has a history of use for neuromuscular complaints and general debility.

Available as powdered extracts, tinctures and dried plant material, muira puama contains compounds such as muirapuamine, tannins and various triterpenes. Some clinical studies have evaluated standardized extracts — often near 1500 mg daily in trials addressing sexual function — but evidence is limited and results vary by individual. Reported precautions include avoidance in pregnancy, lactation and children, and caution for people taking central nervous system or steroid-related medications; infrequent adverse effects reported include insomnia, agitation and occasional respiratory or skin reactions. Consult a healthcare professional for personalized advice.

At a Glance

Muira puama is an Amazonian shrub whose bark and root have long been used in South American herbal traditions as a restorative tonic. Traditionally cited for antifatigue and aphrodisiac uses, it appears in tinctures, infusions and standardized extracts.

Effects and experiences may vary between individuals.

Common name
  • Muira puama
  • Marapauma
Scientific name Ptychopetalum olacoides
Plant family Ptychopetalum olacoides
Origin South America (Brazilian Amazon)
Parts used
  • Bark
  • Root
Active compounds
  • Muirapuamine
  • Tannins
  • Triterpenes
Main benefits
  • Tonic
  • Antifatigue
  • Aphrodisiac
  • Stimulant
Available forms
  • Capsule
  • Infusion
  • Tincture
  • Extract

Origin & History

Muira puama is a shrub native to the Brazilian Amazon, occurring mainly in sandy and clay soils and producing small white flowers with a jasmine-like scent. The root and bark are the parts most commonly harvested; both are described in traditional sources as slightly pink and are used in local herbal preparations.

Indigenous Amazonian communities traditionally used muira puama root and bark as a restorative tonic to counter fatigue and physical debility. Historically it has been applied in the region for neuromuscular complaints, rheumatism, flu and astenia, and its extracts later entered wider herbal use abroad for tonic and digestive purposes; in contemporary herbal practice it is often cited for tonic and aphrodisiac uses. Uses and effects may vary by individual.

Composition & Active Compounds

Muira puama is a shrub up to 5–8 metres tall with white, jasmine-scented flowers; the roots and bark are slightly pink and are the parts most commonly harvested for herbal use. Its chemical profile comprises a mix of alkaloids, tannins, terpenes, esters, volatile oils and other phytochemicals that help explain its traditional applications and make it a subject of phytochemical research. The root and bark are the primary parts used in supplements, and muirapuamina together with tannins are considered key constituents.

  • Muirapuamina: an alkaloid cited as a principal active compound and of interest in research related to the plant’s traditional uses
  • Flobafenos: pigments formed by oxidation of tannins; contribute to coloration and phytochemical complexity
  • Alpha- and beta-resinic acids: resinic acids present among the plant’s acidic constituents
  • Behenic acid (esters): part of the plant’s ester fraction and fatty acid profile
  • Lupeol: a triterpene commonly found in plant resins and triterpenoid fractions
  • Sterols: plant sterols present in the lipid fraction
  • Tannins: polyphenolic compounds contributing astringency and potential antioxidant activity
  • Coumarins: benzopyrone-type compounds reported in the composition
  • Monoterpenes: volatile aromatic compounds contributing to the plant’s scent
  • Triterpenoids: diverse terpenoid compounds including lupeol
  • Volatile oils: essential oil components responsible for aroma
  • Fatty acids: various long-chain fatty acids found in roots and bark
  • Chromium: trace element reported among the plant’s micronutrient content

Properties & Effects

Traditionally, muira puama has been regarded as a restorative herb used to support energy and vitality. Research and traditional use most notably support its use as an aphrodisiac and tonic for sexual function, though individual responses vary.

  • Tonic: may support overall vitality and recovery from temporary physical weakness.
  • Antifatigue: may help reduce feelings of temporary fatigue or debility.
  • Aphrodisiac: may support sexual desire and aspects of sexual function in some people.
  • Stimulant: may support short-term increases in energy or alertness.
  • Antioxidant: research suggests it may help protect cells from oxidative stress.
  • Neuroprotective: research suggests it may support aspects of nervous system health and memory in some contexts.

Dosage & How to Use

Practical dosages for muira puama vary by product; limited clinical dosing information is available.

Erectile dysfunction About 1500 mg daily

Safety, Side Effects & Contraindications

Muira puama should be used with caution in certain groups because comprehensive safety data are limited. People with specific sensitivities, those taking certain medications, and anyone with serious medical conditions are commonly advised to seek professional guidance before use.

Reported side effects are uncommon but can include insomnia, agitation, respiratory disturbances and skin reactions; individual responses vary. Interactions or increased risk are noted for people using steroid medications, treatments that affect the central nervous system, and those with hormone-sensitive conditions or cardiovascular disease, so medical advice is recommended if any of these apply.

  • Allergy to Oleaceae family: avoid if known allergy to plants in this family.
  • Pregnancy and lactation: use is not recommended due to limited safety data.
  • Children under 18: use is not recommended.
  • Steroid medications: take under medical supervision if using steroid treatments.
  • Treatments affecting the central nervous system: exercise caution and consult a clinician if on CNS-active drugs.
  • Hormone-sensitive conditions: caution advised for patients with hormone-sensitive cancers or endometriosis.
  • Hypertension or heart disease: use with caution and under medical advice.

May interact with steroid or CNS medications and is not recommended during pregnancy, lactation or for children; consult a healthcare professional before use, especially if you have hormone-sensitive conditions or cardiovascular disease.